Capillogain® Anti-Hairloss Tonic

Procyanidin B-3

has the potential to counteract the hair growth inhibitory effect of Transforming Growth Factor beta 1 (TGF-beta1)

http://www.ncbi.nlm.nih.gov/pubmed/12473061

http://www.ncbi.nlm.nih.gov/pubmed/10084307

http://www.ncbi.nlm.nih.gov/pubmed/20568787

http://www.ncbi.nlm.nih.gov/pubmed/22253995

http://www.ncbi.nlm.nih.gov/pubmed/22629448

http://www.ncbi.nlm.nih.gov/pubmed/21717518

gamma-Linolenic Acid (GLA)

inhibits 5-alpha Reductase (5AR) type 1 and 2,

counteracts inflammation

http://www.ncbi.nlm.nih.gov/pubmed/9242500

http://rd.springer.com/article/10.1007/BF01986575

http://shikai.com/publications/GLA-A%20Natural%20AntiInflammatoryAgent.pdf

Rasperry Ketone

upregulates Insulin-like Growth Factor 1 (IGF-1) expression

http://www.ncbi.nlm.nih.gov/pubmed/18321745

http://www.ncbi.nlm.nih.gov/pubmed/21839661

Asiasari Radix Extract

upregulates Vascular Endothelial Growth Factor (VEGF) expression

http://www.ncbi.nlm.nih.gov/pubmed/15862941

Triaminodil® (Proderma S.r.l. – Italy)

has nearly the same chemical structure as Minoxidil and a similar spectrum of effects

poster P-186 on page 93:http://www.nahrs.org/home/Portals/0/meetings_support/abstracts_5th_congress/Final_Program_from_Bristol.pdf

http://www.ncbi.nlm.nih.gov/pubmed/21689115

Triaminodil-Monograph (contains several clinical trials)

recent clinical study (the product Aminotril contains the active agent Triaminodil)

Sophora Flavescens Extract

upregulates IGF-1 and Keratinocyte Growth Factor (KGF) expression,

inhibits 5AR type 1 and 2,

inhibits Prostaglandin D2 (PGD2) synthesis,

has antibacterial effects, amongst others against Propionibacterium acnes

http://www.ncbi.nlm.nih.gov/pubmed/12354419

http://www.ehrs.org/conferenceabstracts/2001tokyo/researchabstracts/089-takahashi.htm

http://www.ncbi.nlm.nih.gov/pubmed/10654410

Red Ginseng Root Extract

inhibits 5AR,

upregulates VEGF expression

http://www.ncbi.nlm.nih.gov/pubmed/21538628

http://www.ncbi.nlm.nih.gov/pubmed/12916080

http://www.ncbi.nlm.nih.gov/pubmed/22505819

http://www.ncbi.nlm.nih.gov/pubmed/9627805

http://www.ncbi.nlm.nih.gov/pubmed/12655795

Creatine

supports the energy production of cells,

protects mitochondria from generation of Reactive Oxygen Species (ROS) and thereby reduces cell suicide (apoptosis)

http://www.ncbi.nlm.nih.gov/pubmed/16098029

L-Arginine

upregulates Nitric Oxide (NO) expression and

thereby increases blood flow to the hair follicles

and decreases TGF-beta expression,

gets metabolized to growth-stimulatory polyamines,

gets incorporated into hair shaft as a build block amino acid

http://www.ncbi.nlm.nih.gov/pubmed/16239590

http://www.ncbi.nlm.nih.gov/pubmed/17728935

http://www.ncbi.nlm.nih.gov/pubmed/19841582

Cyanocobalamin

works synergistically with Minoxidil

http://www.ehrs.org/conferenceabstracts/2006london/researchabstracts/14-park.htm

Biotin

Biotin is an essential micronutrient for normal cellular functions.

Biotin deficiency leads to pathologic dermatologic changes in the skin and its appendages.

http://www.ncbi.nlm.nih.gov/pubmed/22444695

http://www.ncbi.nlm.nih.gov/pubmed/12603856

http://www.ncbi.nlm.nih.gov/pubmed/20301497

Hinoki Oil

upregulates VEGF expression,

has antibacterial and antifungal effects

http://www.sciencedirect.com/science/article/pii/S0367326X09001452

Phosphatidylcholine

gets converted to Phosphatidic Acid which in turn

neutralizes the growth-inhibiting effects of TGF-beta1

and protects the cells from apoptosis

http://www.ncbi.nlm.nih.gov/pubmed/12925199

http://www.functional-products.net/en/produkte/capillogain-tonic/