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Dr.Rassman wrote: I do not have direct knowledge of this. It would be best to take the drug at the prescribed 1 mg dose (Propecia) rather than cutting the 5mg dose, but many people who switch from the 1mg dose to the 5mg dose (cutting the tablet into quarters) tell me that they get the same benefits. I would doubt that the acid would react differently with the intact 1mg Propecia and the cut sections of the 5mg tablet, but I do not know for sure. So just to be clear, my answer is just speculation based on what I have been told by users of finasteride.