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    Anonymous
    Inactive
    Nu har jag använt ketokonazolschampoo under drygt två veckor. Märker av en signifikant minskad sexlust, dessutom står den dåligt.

    Varför står det inget om det här i bipacksedeln? Är 100 % säker på att det har med schampoot att göra.

    http://www.ncbi.nlm.nih.gov/pubmed/4040740

    Ketoconazole, an antifungal drug, causes gynecomastia in some patients. It also inhibits androgen and glucocorticoid synthesis. In four volunteer male subjects, 600-mg doses of ketoconazole depressed serum testosterone concentrations markedly, but serum estradiol to a much lesser degree. The bound and free percentages of both hormones were not significantly altered. The net result was a significant elevation of the estradiol-testosterone ratio, expressed as either total circulating hormone or free hormone. In five male patients receiving long-term high-dose ketoconazole therapy, the testosterone concentrations fell, but the effect on estradiol was variable. In these patients the estradiol-testosterone ratio was persistently increased. Since gynecomastia appears to be the result of an elevated estradiol-testosterone ratio, the selective hormonal effect demonstrated may explain the side effect of gynecomastia after ketoconazole therapy.